In Macbeth, Shakespeare presents the theme of guilt as an overwhelming force causing distress to the characters. This is evident when Lady Macbeth says "Out damned spot! Out, I say!". Shakespeare uses the repetition of the word "out" to show Lady Macbeth's desperation and loss of control. The symbolism of a blood stain highlights Lady Macbeth's mental corruption because she sees evidence of her crime all the time to remind her, implying she is responsible. This contrasts with her certainty earlier in the play that "a little water clears us of this deed". Shakespeare uses this to suggest to a Jacobean audience that they should not be like Lady Macbeth, that women should stick to their femininity because when they don't they commit heinous crimes, causing them to receive consequences like Lady Macbeth's mental deterioration. This is because by rejecting gender norms, Lady Macbeth has begun to disrupt God's natural order which is why she suffers her consequences. In Macbeth, Shakespeare presents the theme of guilt as an overwhelming force that distresses the characters. This is evident when Lady Macbeth says "will these hands ne'er be clean?". Shakespeare uses the word "ne'er" to show Lady Macbeth's realisation that she is no longer in control and the consequences will stick with her forever, they are eternal and inescapable, she will never be free from the torment. This contrasts with her strong beliefs that " a little water clears us of this deed", she had not anticipated her mental deterioration because she no longer has that influence. This suggests to a Jacobean audience that disrupting God's natural order will bring psychological collapse. In Macbeth, Shakespeare presents the theme of guilt as an overwhelming force that distresses the characters. This is evident when Macbeth asks "will all great Neptune's oceans wash this blood clean from my hand?". Shakespeare uses the symbolism of "blood" to show guilt in both Lady Macbeth and Macbeth, as they struggle to remove the hallucination of their actions from their hands. Shakespeare uses the idea of "Neptune" as he is a God, implying even divine power cannot save them, showing that guilt is beyond religious purification. The hyperbole of "all great Neptune's oceans" shows Macbeth's overwhelming guilt. This shows that they will have to suffer from an inescapable burden and psychological consequences. This suggests to a Jacobean audience that disrupting God's natural order leads to divine punishment. In Macbeth, Shakespeare presents the theme of guilt as an overwhelming force that distresses the characters. This is evident when Macbeth hears "Macbeth doth murder sleep". Shakespeare uses the word "murder" to highlight that because Macbeth murdered Duncan he has also murdered his ability to sleep so that he has to live in his guilt, implying it is is inescapable. During sleep, people are peaceful and innocent, the idea that Macbeth no longer gets to experience this shows he has murdered his inner peace and security. This suggests to a Jacobean audience that disrupting God's natural order will lead to torment.